Zhihua Tian

Ph.D. Student in AI for Life Sciences · Westlake University

Zhihua Tian portrait

AI for Life Sciences · Biomolecular Design · Computer Vision · Large Language Models

Starting in 2026, I am pursuing a Ph.D. in AI for Life Sciences at Westlake University under the supervision of Prof. Yefeng Zheng.

My research focuses on AI for Life Sciences, spanning biomolecular design, medical AI, computer vision, and multimodal scientific modeling. I work on problems where robustness, interpretability, and reproducibility matter as much as raw accuracy, from 3D molecular generation for binder design to clinically meaningful Parkinson’s disease assessment from smartphone videos and motion data.

News

  • 2026: Our paper “PRIME: A Pretrained Representation–Induced Model for 3D Molecules in De Novo Binder Design” was accepted to the SIGKDD 2026 AI4Sciences Track.
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selected publications

  1. PRIME: A Pretrained Representation–Induced Model for 3D Molecules in De Novo Binder Design
    Zhihua Tian* , Jiale Zhou* , Rubo Wang , Yidong Song , Zhenchao Tang , Tianxu Lv , Zhijian Wu# , Yefeng Zheng#
    * Equal contribution / # Corresponding authors
    SIGKDD 2026 AI4Sciences Track, 2026
    Source Code
  2. Deep learning-enabled accurate assessment of gait impairments in Parkinson's disease using smartphone videos
    Jianda Han* , Zhihua Tian* , Jialing Wu* , Kai Zhang , Shaohua Li , Fahd Baig , Peipei Liu , Ravi Vaidyanathan , Francesca Morgante , Weiguang Huo
    * Equal contribution
    npj Digital Medicine, 2026 IF 15.1
    Source Code
  3. IMU2SKE: Hierarchical Contrastive Learning-Empowered Video-Based Detection of Freezing of Gait in Parkinson's Disease
    Zhihua Tian , Yanwei Zhao , Jianda Han , Weiguang Huo
    In IEEE CBS, 2025
    Source Code

projects

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Voice agent

A full-duplex, real-time voice agent for hospital appointment workflows, with interruptible interaction and an LLM backend.

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romanti.cc

An education-email-based campus social platform centered on signal-based matching, direct chat, and trusted student identity.

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FAGI-PD

FAGI-PD is an intelligent gait analysis platform for Parkinson’s disease screening and management, built on our research published in npj Digital Medicine …

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